Tumors gobble up nanoparticles

A nanoparticle drug delivery system designed for brain tumor therapy has shown promising tumor cell selectivity in a novel cell culture model devised by University of Nottingham scientists. 

The nanoparticles used in this study were prepared from a novel biodegradable polymer poly(glycerol adipate). The polymer has been further modified to enhance incorporation of drugs and make the nanoparticles more effective.

Gold nanoparticles may pan out as tool for cancer diagnosis

When it comes to searching out cancer cells, gold may turn out to be a precious metal.

Purdue University researchers have created gold nanoparticles that are capable of identifying marker proteins on breast cancer cells, making the tiny particles a potential tool to better diagnose and treat cancer. The technology would be about three times cheaper than the most common current method and has the potential to provide many times the quantity and quality of data, said Joseph Irudayaraj, an associate professor of agricultural and biological engineering.

Multifunctional nanoparticle platforms for targeting and imaging cancer cells

 

here has been much recent interest in how nanotechnology will impact the field of medicine. Unfortunately, a number of promising nanostructured systems have turned out to be extremely toxic to humans, thus precluding their use in clinical applications and dashing hopes of an early success for the interdisciplinary field of nanobiotechnology. Now a group of researchers at the University of Michigan Nanotechnology Institute for Medicine and Biological Sciences have devised a multifunctional nanoparticle platform comprising nanoparticles synthesized within dendrimers equipped with targeting molecules and dyes. These dendrimer nanoparticle systems are able to seek out and specifically bind to cancer cells.